well at the moment I'm playing through Killer 7, Eternal Darkness, and Phantom Dust on the consoles
on PC I'm playing Galshell: BloodRedSkies, and Cactus Arcade
handheld wise It's Castlevania: Dawn of Sorrow, and Rhythm Tengoku [had to import it sadly]
Killer 7 is pretty crazy, even trying to describe it would probably give it away.
I am really liking Eternal Darkness. I never had the chance to play it when it first came out. Basically you try to piece together what is going on the first few chapters, but later it all starts to make since. The game has a very unique way of progressing the game by way of chapter pages.
Phantom Dust caught my eye simply because the story and gameplay are completely unusual, The graphics are amazing and the music fits well with the setting [even though you can use your own music in the game]. Think of it like final fantasy tactics, but everyone has psychic powers, the fighting is real time, you can destroy your surroundings, and the story itself is worth playing.
Hm Galshell is a japanese space shooter. But unlike the countless others I played, this one would probably freak some people out [go ahead and search it but I've warned you]. The game itself is kinda textbook. Upgrades to weapons and such depend on how much enemy cells you can gather. I was really close to beating the game, but that last boss -_-. Though after playing each mode, I still have this feeling that normal mode and hard mode are a bit unbalanced [I can beat the first boss in hard mode yet in normal mode I have a bit of trouble.] So far the best mode [in my taste anyway] is omake mode which is much faster than any of the other ones and a bit harder as well.
Cactus Arcade is just a game collection gallery program that links up with games made by Cactus. Depending on your style of gameplay Cactus Arcade has a game for you. http://playthisthing.com/cactus-arcade
This one is really unique, I learned about them through playing the mondo series at a friends house.
I'm a pretty huge Castlevania fan, so of course Dawn of Sorrow is something I'll be playing for a while. I can't wait for their next game 'Order of Ecclesia'
Rhythm Tengoku is, at heart, warioware on super acid. You play though a song like in other rhythm games. However, you also have to complete a task to the beat of the music. After completing a list of tasks, a 'mix' will appear [similar to the boss battles in warioware] placing all of the tasks you just completed into a music video/boss battle. I really like the idea, I hope they bring the game over to the US like they did with Ouendan.